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  How to Clean Your NIOSH  N95  Mask in 3 Easy Steps NIOSH N95 Mask Care: Three Simple Steps Current research published in The Journal of Infectious Diseases demonstrates that these masks may be reused up to three times if they are kept in a clean, dry environment between uses. One expert who participated in the study estimates that some types of masks can be reused up to 10 times before they need to be thrown away. Cleaning your N95 mask properly can help stop the spread of diseases like the flu and TB if you're required to wear one for your job. When you're done wearing your  NIOSH N95  mask for the day, clean it in one of three ways. Before you do anything else, fill your mask to the brim with rubbing alcohol. This eliminates 99. 9 percent of all bacteria, fungus, and viruses. Take off your mask and set it in a cool, dry place to air out. For very dirty tasks, you may want to consider drying it with a second clean, lint-free towel or an air weapon (never impa...